Clinically,
these lesions appear quite similar to conjunctival interepitheliul
neoplasms, although they may show more extensive encroachment onto the
cornea (#21898).Pathologically,
these lesions are characterized by a marked dysplasia of the epithelium
which has invaded through the epithelial basement membrane(#21900).These may be sub-classified as microinvasive which involves
only the substantia propria or invasive which can involve the cornea,
sclera, eyelid, or even orbit.The
deep squamous cells may show signs of dyskeratosis and may also form nests
with central keratin pearls (#21901).