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Acanthamoeba

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Acanthamoeba is a rear but potentially very serious corneal infection that has been bost frequently associated with contact lens wear.  Acanthamoeba organisms are ubiquitous, free-living protozoans which are found naturally in soil and fresh water.  Contamination of contact lens care systems is often the source of infection.  Clinically, acanthamoeba keratitis is characterized by a chronic course with waxing and waning of the infection.  Progression of this infection may lead to a ring-shaped infiltrate of the cornea with infiltrates along the corneal nerve and a large degree of associated pain (#22192).  The clinical diagnosis is often difficult, and this condition may clinically be confused with fungal or herpetic keratitis.  Histopathologically, the corneal stroma is invaded with multiple acanthamoeba cysts, as well as trophozoites, in areas of stromal necrosis and inflammation (#22193).

 

Clinical Photo #22192 High Power #22193
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