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Bacterial Ulcer

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Bacterial ulcers often show initial destruction of epithelium and Bowman's layer followed by varying degrees of stromal destruction which is enhanced by collagenase produced by the injured epithelial cells, keratocytes, and inflammatory cells.  The onset is acute and may be rapidly progressive(#21936).  Pathologically, the infiltrate is composed of acute inflammatory cells such as polymorphoneutrophils (PMN's) (#21939).  The stroma shows collagen necrosis.  The epithelium terminates abruptly at the margin of the ulcer.  Common agents include Staph aureus (#22037), Pneumococcus, Strep, E.  coli, Proteus, Klebsiella, and Pseudamonas (#22040).  If not treated properly, this entity may lead to corneal perforation (#21937) or extensive scarring. 

 

Clinical #21936 Med. Power #21939
21936.jpg (154519 bytes) 21939.jpg (136574 bytes)
Low Power #21937
21937.jpg (94169 bytes)
 
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John A. Moran Eye Center 50 North Medical Drive Salt Lake City UT 84132
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