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Fungal Ulcers

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These lesions have a more insidious onset, seen at 8-15 days after trauma usually involving vegetative material.  Agents include Candida, Aspergillus, Cephalosporium, and Fusarium.  Clincally, the lesion is usually associated with a hypopyon, has satellite lesions around the ulcer, and has an immune ring of Wessely (PMNs and plasma cells surrounding the central lesion with an intervening area of uninvolved tissue) (#21940).  Histologically, its appearance is similar to bacterial ulcer except one often sees eosinophils and may see a granulomatous response.  Special stains are required to see the fungal elements (#21942).

 

Clinical #21940 High Power #21942
21940.jpg (137595 bytes) 21942.jpg (145977 bytes)
 
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