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Phacoanaphylactic Endophthalmitis

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Phacoanaphylactic endophthalmitis is an inflammatory ocular condition secondary to rupture of the lens capsule, either traumatically or iatrogenically.  This disease is thought to be due to an autoimmune process by which previously sequestered lens proteins are liberated or release through a ruptured lens capsule leading to an autosensitization.  Histopathologically, this condition is characterized by a zonal, granulomatous inflammation which surrounds the area of ruptured lens capsule and cortical material(#22213, #22214).  The innermost part of the reaction consists of polymorphonuclear cells and multi-nucleated giant cells.  Finally, the outer-most layer of this zonal inflammation consists of lymphocytes and plasma cells which surround the epithelioid cells.

 

 

 

Low Power #22213 Med. Power #22214
22213.jpg (139191 bytes) 22214.jpg (127999 bytes)
 
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