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Actinic Keratosis

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Clinically, these lesions may appear as irregularly thickened or elevated skin which may have a brown or reddish discoloration with thickening of the epithelium.  Histologically, the epithelium may show signs of acanthosis and hyperkeratosis (#21844).  In addition, cellular atypia of the innermost layers of the squamous epithelium is common; however, normal polarity and maturation are preserved.  The superficial dermal tissue shows a characteristic basophilic degeneration of collagen (#21846).

 

 

High Power #21846 Med Power #21844
21846.jpg (100351 bytes) 21844.jpg (143704 bytes)
 
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John A. Moran Eye Center 50 North Medical Drive Salt Lake City UT 84132
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