Nevi
may be congenital or acquired.Most
nevi of the lids are acquired (#21867).Histologically, nests of nevus cells may be present at the
interface of the epidermis and dermis (junctional nevus), but with time,
the nevus cells will migrate into the dermis (compound nevus), and the
lesion may become elevated.Finally,
the nevus cells may lose all connection with the overlying epidermis to
lie entirely within the dermis (dermal nevus) (#21868); the lesion at this
point is generally elevated and may be amelanotic.The nevus cells tend to have bland-appearing nuclei with very
minimal nuclear activity or mitoses and may often be multi-nucleated
(#21870).These cells will form into nests in the dermal tissue
separated by fine fibrous septa.
