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Sebaceous Gland Carcinoma

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Adenocarcinoma of sebaceous glands presents as a wide spectrum of clinical appearances and can be easily mis-diagnosed as a more common entity such as a chalazion or a chronic blepharoconjunctivitis (#21861) (#21862).  The upper eyelid is most common site of sebaceous CA in the body.  These tumors can arise from the meibomian glands or the glands of Zeis.  Histologically, the degree of cellular anaplasia varies (#21864).  Poorly differentiated tumors can be mistaken for squamous or basal cell carcinoma.  Many of the tumor cells stain positively for fat, which makes lipid staining of frozen tissue important (#21865).  These tumors are potentially agressive and may metastasize.  

 

-See also (#28061, #28064, #28193, #28196, #28199) for other views of sebaceous gland carcinoma of the eyelid.

 

Clinical #21861 Clinical #21862
21861.jpg (93732 bytes) 21862.jpg (81115 bytes)
High Power #21864 High Power #21865
21864.jpg (98072 bytes) 21865.jpg (78717 bytes)
 
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