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congenital anomalies of the optic nerve may lead to an oblique,
horizontal, or tilted disc, often with the appearance of an inferior conus(#22237).
A more serious congenital defect of the optic nerve is an optic
nerve coloboma. A coloboma is
a unilateral abnormality of the optic nerve head thought to be secondary
to a failure of fusion of the posterior part of the embryonic fissure.
A complete optic nerve coloboma may form a large hole or posterior
protrusion in the area of the optic nerve(#22238).
Histopathologically, a coloboma is seen as a large defect with
mostly bare sclera and a small amount of fibrous tissue or gliosis lining
the defect. The retina and choroid along the edges of the coloboma may
also be involved. Another
form of an optic nerve coloboma is the so-called morning glory syndrome
which is characterized by a large excavation of the optic nerve head that
resembles the morning glory flower(#22240).
-For other
slides of morning glory syndrome, see (#27968, #27971)
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| Fundus
Photo #22237 |
Fundus
Photo #22238 |
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| Fundus
Photo #22240 |
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