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Meningioma

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The most common primary site of this tumor is intracranial, and it invades the orbit secondarily.  Less commonly, it arises intraorbitally around the optic nerve.  Orbital meningiomas are more common in middle-aged females.  They tend to be more aggressive tumors in children.  Clinically, these lesions commonly present with a painless decrease in visual acuity and progressive exophthalmos.  They present less commonly with visual field loss, optic atrophy, optociliary shunt vessels, lid edema, muscle palsies, retinal striae, hypertophy or hyperostosis of the bony orbit.  There is also a small increased incidence in von Recklinghausen's disease.  Clinically, an optic disc exam may reveal disc edema, or disc atrophy with optociliary shunt vessels (#22108).  Pathologically(#22110), these tumors may show several histologic patterns including meningotheliomatous or syncytial (large, uniform cells with indistinct boundaries forming solid sheets) and psammomatous (whorled pattern of concentric cell layers (#22111).  The central core of some nests become hyalinized and calcified forming psammona bodies (#22112)-- fibroblastic, angioblastic, or mixed. 

 

-(#23339) shows the effects of a meningioma on the optic nerve.

 

Clinical #22108 Gross #22110
22108.jpg (258601 bytes) 22110.jpg (85992 bytes)
High Power #22111 Med. Power #22112
22111.jpg (99344 bytes) 22112.jpg (101156 bytes)
 
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John A. Moran Eye Center 50 North Medical Drive Salt Lake City UT 84132
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