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Orbital Hemangiopericytoma

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A rare neoplasm originating from pericytes which are cells in walls of capillaries and venules external to endothelial cells and enveloped by a basement membrane.  The tumor is usually small and singular, with more frequent symptoms than a capillary hemangioma and more vascularity (#22120).  This lesion frequently may recur after incomplete excision and may potentially undergo a malignant transformation which may metastasize to lungs, bone, liver, and regional nodes.  Histopathologically, this lesion consists of numerous capillary channels in a sinusoidal or staghorn pattern surrounded by solid areas of spindle-shaped or round cells with uniform cellular morphology (#22123) (#22122).  A reticulin stain is often helpful to outline the basement membrane.

 

Clinical #22120 High Power #22123
22120.jpg (67447 bytes) 22123.jpg (179671 bytes)
Med. Power #22122
22122.jpg (206493 bytes)
 
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