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| Cystoid
macular edema (CME) is seen most commonly following surgical procedures
such as cataract extraction and secondary to retinal vascular disease such
as diabetic retinopathy and retinal venous occlusions.
In addition, ocular inflammation, medications, and tumors may lead
to the formation of cystoid macular edema.
Exudative or transudative fluid (from retinal vascular leakage in
the perifoveal area) collects in the loosely- packed outer plexiform layer
of Henle. Clinically, this
produces a stellate or flower petal pattern on fluorescein angiography due
to the horizontally- oriented fibers in the outer plexiform layer of the
macula(#22066, #22068). Ophthalmoscopy
using a red-free light reveals a honeycomb appearance corresponding to the
walls of the fluid-filled cavities. These
spaces may coalesce producing a macular retinoschisis or a hole. Histopathologically, this exudative fluid in the outer
plexiform layer is seen as an amorphous eosinophilic material or as
multiple blank spaces(#22069,22071).
(#22745,
#22747, #23132) are other views of cystoid macular edema.
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| Clinical
#22066 |
Gross
#22068 |
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| Med.
Power #22069 |
Low
Power #22071 |
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