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Cytomegalovirus

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Cytomegalovirus infection or cytomegalic inclusion disease may occur congenitally but is most commonly seen in the acquired form.  This acquired infection is noted most commonly in patients with immunosuppression secondary to tumors, chemotherapy, transplantation, or AIDS infection.  Clinically, this condition is characterized by an extensive retinitis with sharply defined borders.  This lesion has often been described as a "brush fire" with large areas of  necrosis and hemorrhage of the retina(#22232).  Histopathologically, this condition is characterized by a cagulative, necrotizing retinitis.  Often there is a secondary diffuse inflammation of the choroid underlying this lesion(#10634).  The retinal cells infected by this organism show large intranuclear inclusion bodies, as well as small intracytoplasmic inclusion bodies.

 

-(#22925, #22928, #22931, #22934, #22937, #22940, #22943) are all slides of cytomegalovirus induced retinitis.

 

-Other views of cytomegalovirus found in AIDS patients can be seen in slides (#32353, #32355, #32364, #32368, #32371, #32376, #32377, #32386, #32391, #32444, #32445).

 

Fundus Photo #22232 Medium Power #10634
22232.jpg (51012 bytes)
 
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