Pigmented
iris epithelial cysts may arise from the posterior pigment epithelium of
the iris, on the posterior surface, or at the pupillary margin.These cysts are usually benign and attached to the iris, although
on occasion a cyst may break loose and become free-floating, possibly
causing pupil obstruction or secondary angle closure glaucoma.These cysts are often pigmented and may give the appearance of a
malignant melanoam of the iris(#22241).Histopathologically, these cysts are lined by epithelial cells from
the posterior pigment epithelial layer of the iris(#22243, #22244).