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| Sarcoidosis
is a systemic granulomatous disease shich most commonly affects black,
young adults. The most common
ocular inflammation seen in sarcoidosis is an anterior uveitis.
This is a granulomatous type of uveitis which is characterized by
large "mutton-fat" keratic precipitates on the cornea.
In addition, there can be large nodule of the iris present, along
with extensive posterior synechiae formation(#22246).
Posterior inflammation may involve both the retina and the choroid
with the classic picture of retinal peri-phlebitis forming "candle
wax drippings." Histopathologically,
sarcoidosis is characterized by a non-caseating, granulomatous
inflammation with descrete foci of inflammation.
These small foci of granulomatous inflammation on the surface of
the iris may form koeppe nodules(#22247, #22249).
In addition, the epithelioid cells in the granulomos may have
small, eosinophilic, star-shaped inclusions called asteroid bodies or
darker ovoid inclusions called Schaumann's bodies.
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| Slit
Lamp Photo #22246 |
Low
Power #22247 |
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| High
Power #22259 |
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