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| Pigmented
nevi of the iris are often seen clinically.
These are characterized by discretely pigmented, elevated lesions
found on the surface of the iris (#22266).
On occasion, thses lesions may give rise to a malignant melanoma of
the iris and should be followed regularly for signs of growth which may
lead to suspicion for malignant melanoma.
Histopathologically, the nevus is characterized by a proliferation
of benign melanocytes arising from the neural crest-derived melanocytes of
the anterior iris stroma. Previously,
many lesions which were called malignant melanomas of the iris have been
reclassified as nevi. Iris
nevi may be composed predominantly of spindle cells with varying degrees
of atypia, as well as spindle cells which form a surface plaque (#22267,
#22269). In addition, the
nevi may be composaed of epithelioid cells, or may be a mixture of both.
Views of
choroidal nevus can be seen on the following slides: (#22680, #22683,
#22713, #22719, #22722)
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| Clinical
Photo #22266 |
Medium
Power #22267 |
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| High
Power #22269 |
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