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Edward Zamrini, M.D.

Professor of Neurology
Center for Alzheimer’s Care, Imaging and Research (CACIR)

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Edward Y. Zamrini, M.D.

Improving Alzheimer’s Treatments

Dr. Edward Zamrini is board certified in Geriatric Neurology and Behavioral Neurology & Neuropsychiatry. He has over 24 years of experience in clinical care, education and research for Alzheimer’s and related neurodegenerative diseases, and has gained a broad expertise as an investigator in well over 50 clinical studies.

Detecting Alzheimer's before symptoms appear is one of Dr. Zamrini's primary goals. "Research into early diagnosis and therapeutic intervention can help us to lessen the impact of the disease and, ultimately, delay or prevent it," he says. He urges people not to wait if they suspect that something is awry, because early diagnosis can enable application of more effective therapies and management.

Academic History

Dr. Zamrini joined the University of Utah faculty in 2006 as Professor in the Department of Neurology at the University of Utah School of Medicine in the Center for Alzheimer’s Care, Imaging and Research (CACIR), where he also served as Director of Clinical Trials from 2006-2011. In addition, Dr. Zamrini is a member of the University’s Center on Aging and a Scientist in the University of Utah Brain Institute.

Dr. Zamrini received his M.D. from the University of Beirut in Lebanon. After his internship at the Lutheran Medical Center in Brooklyn, he completed his residency at New York's North Shore University Hospital, where he was chief resident of Neurology. Dr. Zamrini completed fellowships in Epilepsy and in Neurogeriatrics and Behavioral Neurology at the Medical College of Georgia in Augusta, before going on to direct the Geriatric Neuropsychiatry Program at Augusta's VA Medical Center.

Prior to joining the University of Utah in 2006, Dr. Zamrini served as Director of the Clinical and Information Transfer Cores of the NIH-funded Alzheimer's Disease Research Center at the University of Alabama at Birmingham.

Dr. Zamrini is a member of the American Academy of Neurology, American College of Physicians, and New York Academy of Sciences.

Clinical and Research Interests

Dr. Zamrini's clinical interests include dementia and related memory disorders, especially those that are atypical, rapidly progressive, early-onset, focal, or familial.

Dr. Zamrini's research has focused primarily on the clinical features and pathophysiology of Alzheimer's and related neurodegenerative disorders, neuroimaging with PET and MEG, and novel pharmaceutical interventions. He has been an affiliate of the Alzheimer’s Disease Cooperative Study and a member of the worldwide Alzheimer’s Disease Neuroimaging Initiative. Dr. Zamrini is involved in numerous ongoing clinical drug trials, which explore new therapies in various stages of the disease. He and his colleagues also are currently studying novel compounds to aid in early detection and measuring the extent of neurodegenerative disease.

Dr. Zamrini is keenly interested in improving early diagnosis and developing proactive interventions to benefit both patients and caregivers. Dr. Zamrini is familiar with health education needs of patients and their families, and is knowledgeable about community needs having served as a board member of the Augusta Chapter of the Alzheimer’s Association for 6 years and as Chapter President for 2 years. He currently is Principal Investigator of a pilot research study of patient outcomes of Proactive Dementia Care funded by the Center for Health Improvement.

Dr. Zamrini is an active participant in educational programs offered by the Alzheimer’s Association, AARP, and the Osher Lifelong Learning Institute and Brain Institute at the University of Utah. As a member of the Intermountain West’s only academic Alzheimer’s center, he helps train future dementia experts through a Cognitive Disorders mini-fellowship program and regional, national and international continuing education conferences.

Selected Publications

  • Zamrini E, McGwin G, Roseman JM. (2004). Association between statin use and Alzheimer's disease. Neuroepidemiology, 23(1-2), 94-8.
  • Zamrini E, Parrish JA, Parsons D, Harrell LE. (2004). Medical comorbidity in black and white patients with Alzheimer's disease. South Med J, 97(1), 2-6.
  • Zamrini E, De Santi S, Tolar M. (2004). Imaging is superior to cognitive testing for early diagnosis of Alzheimer's disease. Neurobiol Aging, 25(5), 685-91.
  • Zamrini EY. (2006). Emerging Drug Therapies for Dementia. Geriatrics and Aging, 9(2), 107,110-113.
  • Rahman A, Baker PS, Allman RM, Zamrini E. (2007). Dietary Factors And Cognitive Impairment In Community-Dwelling Elderly. Journal of Nutrition, Health and Aging, 11(1), 49-54.
  • Okonkwo OC, Griffith HR, Copeland JN, Belue K, Lanza S, Zamrini EY, Harrell LE, Brockington JC, Clark D, Raman R, Marson DC. (2008). Medical decision-making capacity in mild cognitive impairment: a 3-year longitudinal study. Neurology, 71(19), 1474-80.
  • Zamrini E. (2004). Alzheimer's Disease [Book Chapter]. In Faught RE (Ed), Year in Neurology, 2004. Oxford, Clinical Publishing Services.
  • Zamrini EY, Quicino M. (2009). Other Dementias [Book Chapter]. In Weiner MF, Lipton AM (Eds.), The Dementias: Diagnosis, Treatment and Research. Arlington: American Psychiatric Publishing, Inc.

View a more complete list of Dr. Zamrini's publications here, at PubMed.