Douglas Grossman, M.D., Ph.D.
Associate Professor of Dermatology and Oncological Sciences
B.S., magna cum laude, 1985, Duke University
Ph.D., 1992, Baylor College of Medicine
M.D., Alpha Omega Alpha 1994, Baylor College of Medicine
Residency in Dermatology, 1995-1998, Yale University
Fellowship in Cancer Biology, 1998-2000, Yale University
Board Certification in Dermatology
Clinical and Research Interests
Skin cancer: specializes in patients with melanoma, squamous cell carcinoma, basal cell carcinoma; and patients with family history of melanoma or multiple nevi (moles). Director of Mole Mapping program. Research areas include molecular aspects of melanoma and non-melanoma skin cancer with a focus on apoptosis (programmed cell death) in melanocyte and keratinocyte carcinogenesis, and the role of oxidative stress in melanoma.
Selected Publications
Fuller SR, Bowen GM, Tanner B, Florell SR, Grossman D: Digital dermoscopic monitoring of atypical nevi in patients at risk for melanoma. Dermatol Surg in press, 2007.
Thomas J, Liu T, Cotter MA, Florell SR, Robinette K, Hanks AN, Grossman D: Melanocyte expression of Survivin promotes development and metastasis of UV-induced melanoma in HGF transgenic mice. Cancer Res 67:5172-5178, 2007.
Cotter MA, Florell SR, Leachman SA, Grossman D: Absence of senescence-associated b-galactosidase activity in human melanocytic nevi in vivo. J Invest Dermatol in press, 2007.
Liu T, Biddle D, Hanks AN, Brouha B, Yan H, Lee RM, Leachman SA, Grossman D: Activation of dual apoptotic pathways in human melanocytes and protection by Survivin. J Invest Dermatol 126:2247-2256, 2006.
Raj D, Brash DE, Grossman D: Keratinocyte apoptosis in epidermal development and disease. J Invest Dermatol 126:243-257, 2006.
Yan H, Thomas J, Liu T, Raj D, London N, Tandeski T, Leachman SA, Lee RM, Grossman D: Induction of melanoma cell apoptosis and inhibition of tumor growth using a cell-permeable Survivin antagonist. Oncogene 25:6968-6974, 2006.
Search PubMed for additional publications
Grossman Laboratory
The Grossman Lab is located on the 5th floor of the Huntsman Cancer Institute at the University of Utah.
