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| These
lesions appear clinically as salmon-colored nodules or patches (#21919).
When the lesion is isolated and histologically shows no
characteristics of malignancy, the diagnosis of benign lymphoid
hyperplasia may be warranted. Malignant
lymphoma of conjunctiva may appear as the first evidence of systemic
lymphoma or as part of widespread involvement.
The histopathologic diagnosis (#21921) of lymphoid lesions can be
quite difficult as many of these tumors fall into a "gray zone"
between obviously benign lymphoid hyperplasia and frank lymphoma.
Surface staining of fresh tissue is often necessary to
differentiate these lesions. Malignant
lymphomas are monoclonal and mostly composed of B-lymphocytes with sheets
of cytologically similar cells with no germinal centers or vascularity,
and no other cells such as plasma cells.
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| Clinical
#21919 |
High
Power #21921 |
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