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| Bacterial
ulcers often show initial destruction of epithelium and Bowman's layer
followed by varying degrees of stromal destruction which is enhanced by
collagenase produced by the injured epithelial cells, keratocytes, and
inflammatory cells. The onset
is acute and may be rapidly progressive(#21936).
Pathologically, the infiltrate is composed of acute inflammatory
cells such as polymorphoneutrophils (PMN's) (#21939). The stroma shows collagen necrosis. The epithelium terminates abruptly at the margin of the
ulcer. Common agents include
Staph aureus (#22037), Pneumococcus, Strep, E.
coli, Proteus, Klebsiella, and Pseudamonas (#22040).
If not treated properly, this entity may lead to corneal
perforation (#21937) or extensive scarring.
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| Clinical
#21936 |
Med.
Power #21939 |
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| Low
Power #21937 |
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