|
| |
|
|
| Retinitis
pigmentosa is a hereditary degenerative disorder which is characterized by
bilateral progressive loss of peripheral vision, night blindness, and
marked ring-like constriction of visual field.
Fundus examination reveals an atrophic, waxy pallor to the optic
disc with marked attenuation of retinal arterials(#22072). The retina itself shows a characteristic bony spicule-shaped
disruption of pigmentation
(#22074).
Histopathologically, this lesion is characterized by migration of
macrophages and RPE cells filled with melanin into the retina, especially
around blood vessels(#22075). This
is thought to explain the bony spicule pattern of pigmentation seen on
fundus examination. In addition, there is an atrophy of the photoreceptors of the
retina as well as the choriocapillaris.
See also
(#22850, #22853, #22856) for other slides of retinitis pigmentosa.
|
| Clinical
#22072 |
Clinical
#22074 |
 |
 |
| Med.
Power #22075 |
|
 |
|
|
|
|
