September 27, 2004

There have been reports of the pantoprazole glass vials breaking when healthcare workers try to connect the vials to spiked intravenous system adaptors. This is a safety concern for anyone preparing or administering pantoprazole injection using these adaptors. More details, including the dear healthcare professional letter and the updated product labeling may be found at:

• http://www.fda.gov/medwatch/SAFETY/2004/safety04.htm#protonix